| VA | From | Airport | To | Destination | Type | Distance miles | Frequency | Competitors | |
|---|---|---|---|---|---|---|---|---|---|
| CIF | HBBA | Bujumbura Intl | LFPO | Paris - Orly | Long | 3424.3 | 0 | ||
| NAE | HBBA | Bujumbura Intl | OMAA | Abu Dhabi Intl | Medium | 2226.2 | 0 | ||
| RSQ | HBBA | Bujumbura Intl | FAOR | Johannesburg Intl | Medium | 1370.2 | 1 | ||
| RSQ | HBBA | Bujumbura Intl | HSSJ | Juba | Regional | 510.2 | 0 | ||
| SAA | HBBA | Bujumbura Intl | FZJH | Isiro-Matari | Local | 383.1 | 1 | ||
| SAA | HBBA | Bujumbura Intl | FZQA | Lubumbashi Intl | Regional | 507.5 | 1 | ||
| SAA | HBBA | Bujumbura Intl | FACT | Cape Town Intl | Medium | 1934.0 | 1 | ||
| SAA | HBBA | Bujumbura Intl | LIML | Milan - Linate | Long | 3115.5 | 1 | ||
| SCA | HBBA | Bujumbura Intl | FWKI | Kamuzu Intl | Regional | 681.1 | 0 | ||
| SCA | HBBA | Bujumbura Intl | HUEN | Entebbe Intl | Local | 275.2 | 0 | ||
| SKA | HBBA | Bujumbura Intl | HSOB | El Obeid | Regional | 989.9 | 0 | ||
| SKA | HBBA | Bujumbura Intl | HSSJ | Juba | Regional | 510.2 | 1 | ||
| SKA | HBBA | Bujumbura Intl | FVHA | Harare Intl | Regional | 882.9 | 1 | ||
| SKA | HBBA | Bujumbura Intl | FWKI | Kamuzu Intl | Regional | 681.1 | 0 |