| VA | From | Airport | To | Destination | Type | Distance miles | Frequency | Competitors | |
|---|---|---|---|---|---|---|---|---|---|
| CIF | KCHS | Charleston AFB/Intl | NTAA | Tahiti I - Faaa | Long | 5001.8 | 1 | ||
| CIF | KCHS | Charleston AFB/Intl | LFPG | Paris - Charles-De-Gaulle | Long | 3674.8 | 0 | ||
| FAA | KCHS | Charleston AFB/Intl | KJAX | Jacksonville Intl | Local | 167.0 | 0 | ||
| JUL | KCHS | Charleston AFB/Intl | KIND | Indianapolis Intl | Regional | 508.4 | 1 | ||
| JUL | KCHS | Charleston AFB/Intl | KORD | Chicago-OHare Intl | Regional | 660.5 | 1 | ||
| JUL | KCHS | Charleston AFB/Intl | KMIA | Miami Intl | Local | 426.5 | 0 | ||
| OSA | KCHS | Charleston AFB/Intl | OMDB | Dubai Intl | Long | 6480.1 | 0 | ||
| OSA | KCHS | Charleston AFB/Intl | KLAS | Las Vegas - McCarran Intl | Medium | 1737.5 | 0 | ||
| OSA | KCHS | Charleston AFB/Intl | CGAS | Brooklyn CGAS | Regional | 547.5 | 1 | ||
| OSA | KCHS | Charleston AFB/Intl | EDDF | Frankfurt/Main | Long | 3874.4 | 0 | ||
| OSA | KCHS | Charleston AFB/Intl | KSFO | San Francisco Intl | Medium | 2075.7 | 0 | ||
| OSA | KCHS | Charleston AFB/Intl | PMDY | Midway Atoll | Long | 4840.0 | 1 | ||
| OSA | KCHS | Charleston AFB/Intl | WMKK | Kuala Lumpur Intl - Sepang | Long | 8659.2 | 2 | ||
| OSA | KCHS | Charleston AFB/Intl | MMUN | Cancun Intl | Regional | 799.6 | 0 | ||
| OSA | KCHS | Charleston AFB/Intl | GMMN | Casablanca - Mohamed V | Long | 3559.9 | 1 | ||
| OSA | KCHS | Charleston AFB/Intl | GVAC | Sal - Amilcar Cabral | Long | 3216.5 | 1 | ||
| OSA | KCHS | Charleston AFB/Intl | KMIA | Miami Intl | Local | 426.5 | 1 | ||
| OSA | KCHS | Charleston AFB/Intl | TXKF | Bermuda Is - Bermuda Intl | Regional | 776.2 | 0 |