| VA | From | Airport | To | Destination | Type | Distance miles | Frequency | Competitors | |
|---|---|---|---|---|---|---|---|---|---|
| AAW | KMFR | Rogue Valley Intl-Medford | EIME | Baldonnel - Casement AB | Long | 4193.0 | 1 | ||
| AAW | KMFR | Rogue Valley Intl-Medford | EGNS | Isle Of Man | Long | 4204.8 | 0 | ||
| AAW | KMFR | Rogue Valley Intl-Medford | RJSC | Yamagata | Long | 4168.4 | 0 | ||
| AVL | KMFR | Rogue Valley Intl-Medford | KORD | Chicago-OHare Intl | Medium | 1544.0 | 0 | ||
| AVL | KMFR | Rogue Valley Intl-Medford | KLAX | Los Angeles Intl | Regional | 547.8 | 1 | ||
| CFC | KMFR | Rogue Valley Intl-Medford | KSFO | San Francisco Intl | Local | 286.2 | 2 | ||
| CFC | KMFR | Rogue Valley Intl-Medford | KPDX | Portland Intl | Local | 193.2 | 2 | ||
| NSA | KMFR | Rogue Valley Intl-Medford | LFMN | Nice/Cote dAzur | Long | 4982.3 | 0 | ||
| NSA | KMFR | Rogue Valley Intl-Medford | KORD | Chicago-OHare Intl | Medium | 1544.0 | 1 | ||
| NSA | KMFR | Rogue Valley Intl-Medford | KMSP | Minneapolis-St Paul Intl | Medium | 1289.5 | 0 | ||
| NSA | KMFR | Rogue Valley Intl-Medford | KMOD | Modesto City-Co-Sham | Local | 298.2 | 0 | ||
| NSA | KMFR | Rogue Valley Intl-Medford | KJAC | Jackson Hole | Regional | 537.2 | 1 | ||
| NSA | KMFR | Rogue Valley Intl-Medford | KJFK | New York - Kennedy Intl | Medium | 2177.4 | 0 | ||
| NSA | KMFR | Rogue Valley Intl-Medford | KLAX | Los Angeles Intl | Regional | 547.8 | 0 | ||
| SCA | KMFR | Rogue Valley Intl-Medford | KEUG | Eugene - Mahlon Sweet | Local | 106.0 | 0 | ||
| SCA | KMFR | Rogue Valley Intl-Medford | KBNG | Banning Mun | Regional | 580.9 | 0 | ||
| SCA | KMFR | Rogue Valley Intl-Medford | KSPB | Scappoose Industrial | Local | 203.9 | 0 | ||
| SCA | KMFR | Rogue Valley Intl-Medford | KSFO | San Francisco Intl | Local | 286.2 | 0 | ||
| SCA | KMFR | Rogue Valley Intl-Medford | KLMT | Klamath Falls Intl | Local | 52.3 | 0 | ||
| SCA | KMFR | Rogue Valley Intl-Medford | KSEA | Seattle-Tacoma Intl | Local | 305.4 | 1 | ||
| SCA | KMFR | Rogue Valley Intl-Medford | KONP | Newport Mun | Local | 142.1 | 0 | ||
| SCA | KMFR | Rogue Valley Intl-Medford | KSIY | Montague - Siskiyou Co | Local | 39.9 | 0 |