| VA | From | Airport | To | Destination | Type | Distance miles | Frequency | Competitors | |
|---|---|---|---|---|---|---|---|---|---|
| AAW | KMSY | New Orleans Intl | KDAL | Dallas Love | Local | 378.4 | 0 | ||
| AAW | KMSY | New Orleans Intl | KLAX | Los Angeles Intl | Medium | 1447.7 | 1 | ||
| ACF | KMSY | New Orleans Intl | MMMY | Monterrey - Gen Mariano Escobedo Intl | Regional | 580.0 | 3 | ||
| ACF | KMSY | New Orleans Intl | KJAX | Jacksonville Intl | Local | 445.1 | 0 | ||
| AEU | KMSY | New Orleans Intl | HECA | Cairo Intl | Long | 5891.8 | 1 | ||
| AEU | KMSY | New Orleans Intl | GMAD | Agadir - Al-Massira | Long | 4092.1 | 0 | ||
| AVL | KMSY | New Orleans Intl | KLAX | Los Angeles Intl | Medium | 1447.7 | 1 | ||
| AVL | KMSY | New Orleans Intl | KORD | Chicago-OHare Intl | Regional | 728.0 | 1 | ||
| FLW | KMSY | New Orleans Intl | LFML | Marseille/Provence | Long | 4411.0 | 3 | ||
| IFR | KMSY | New Orleans Intl | KMIA | Miami Intl | Regional | 585.3 | 0 | ||
| IFR | KMSY | New Orleans Intl | KSAT | San Antonio Intl | Local | 428.5 | 0 | ||
| IFR | KMSY | New Orleans Intl | KAST | Astoria Regl | Medium | 1840.2 | 0 | ||
| IFR | KMSY | New Orleans Intl | KADS | Dallas - Addison | Local | 380.9 | 0 | ||
| JUL | KMSY | New Orleans Intl | KTPA | Tampa Intl | Local | 423.0 | 0 | ||
| NAE | KMSY | New Orleans Intl | VHHH | Hong Kong Intl | Long | 7366.1 | 0 | ||
| NAE | KMSY | New Orleans Intl | KPIE | St Petersburg-Clearwater Intl | Local | 416.5 | 1 | ||
| NAE | KMSY | New Orleans Intl | KSLN | Salina Mun | Regional | 641.8 | 0 | ||
| NAE | KMSY | New Orleans Intl | PMDY | Midway Atoll | Long | 4443.8 | 1 | ||
| NAE | KMSY | New Orleans Intl | TFFR | Pointe-A-Pitre - Le Raizet | Medium | 1779.0 | 1 | ||
| NAE | KMSY | New Orleans Intl | PANC | Stevens Anchorage Intl | Medium | 2974.8 | 1 | ||
| NAE | KMSY | New Orleans Intl | UUDD | Moscow - Domodedovo | Long | 5029.1 | 0 | ||
| NAE | KMSY | New Orleans Intl | OMDB | Dubai Intl | Long | 6940.4 | 0 | ||
| NAE | KMSY | New Orleans Intl | KSUX | Sioux City - Sioux Gateway | Regional | 800.9 | 1 | ||
| NAE | KMSY | New Orleans Intl | KJFK | New York - Kennedy Intl | Medium | 1026.0 | 0 | ||
| NAE | KMSY | New Orleans Intl | MUHA | Havana - Jose Marti Intl | Regional | 594.8 | 0 | ||
| NAE | KMSY | New Orleans Intl | TNCC | Curacao I - Willemstad/Hato Intl. | Medium | 1595.0 | 0 | ||
| OSA | KMSY | New Orleans Intl | KMIA | Miami Intl | Regional | 585.3 | 0 | ||
| OSA | KMSY | New Orleans Intl | KSAT | San Antonio Intl | Local | 428.5 | 1 | ||
| OSA | KMSY | New Orleans Intl | KILM | Wilmington Intl | Regional | 677.6 | 0 | ||
| OSA | KMSY | New Orleans Intl | KLAS | Las Vegas - McCarran Intl | Medium | 1300.2 | 1 | ||
| RSQ | KMSY | New Orleans Intl | ZSSS | Shanghai - Hongqiao | Long | 6710.7 | 2 | ||
| RSQ | KMSY | New Orleans Intl | UUEE | Moscow - Sheremetyevo | Long | 4993.1 | 0 | ||
| SKA | KMSY | New Orleans Intl | CYVR | Vancouver Intl | Medium | 1884.6 | 0 | ||
| SKA | KMSY | New Orleans Intl | SEQM | Quito Aeropuerto Internacional Mariscal Sucre | Medium | 1931.3 | 1 | ||
| SKA | KMSY | New Orleans Intl | KMIA | Miami Intl | Regional | 585.3 | 1 | ||
| SKA | KMSY | New Orleans Intl | KIAD | Washington Dulles Intl | Regional | 828.8 | 0 | ||
| UFA | KMSY | New Orleans Intl | VHHH | Hong Kong Intl | Long | 7366.1 | 0 | ||
| UFA | KMSY | New Orleans Intl | YPDN | Darwin Intl | Long | 8287.1 | 0 | ||
| UFA | KMSY | New Orleans Intl | SBFZ | Fortaleza - Pinto Martins Intl | Long | 3590.5 | 0 | ||
| UFA | KMSY | New Orleans Intl | KDTW | Detroit Metro Wayne Co | Regional | 805.2 | 1 | ||
| UFA | KMSY | New Orleans Intl | SBGL | Rio De Janeiro - Galeao-Antonio C Jobim Intl | Long | 4168.6 | 0 | ||
| UFA | KMSY | New Orleans Intl | LFPG | Paris - Charles-De-Gaulle | Long | 4172.5 | 1 | ||
| UPS | KMSY | New Orleans Intl | LFML | Marseille/Provence | Long | 4411.0 | 0 | ||
| USA | KMSY | New Orleans Intl | KMIA | Miami Intl | Regional | 585.3 | 2 | ||
| USA | KMSY | New Orleans Intl | KLAX | Los Angeles Intl | Medium | 1447.7 | 0 |