| VA | From | Airport | To | Destination | Type | Distance miles | Frequency | Competitors | |
|---|---|---|---|---|---|---|---|---|---|
| CFC | KPSM | Portsmouth - Pease Intl Tradeport | KSYR | Syracuse Hancock Intl | Local | 231.4 | 4 | ||
| CFC | KPSM | Portsmouth - Pease Intl Tradeport | KJFK | New York - Kennedy Intl | Local | 197.1 | 3 | ||
| FAA | KPSM | Portsmouth - Pease Intl Tradeport | EIDW | Dublin Intl | Medium | 2559.0 | 0 | ||
| FAA | KPSM | Portsmouth - Pease Intl Tradeport | WMKK | Kuala Lumpur Intl - Sepang | Long | 8021.1 | 0 |