| VA | From | Airport | To | Destination | Type | Distance miles | Frequency | Competitors | |
|---|---|---|---|---|---|---|---|---|---|
| AVL | KSAT | San Antonio Intl | KORD | Chicago-OHare Intl | Regional | 905.1 | 1 | ||
| AVL | KSAT | San Antonio Intl | KLAX | Los Angeles Intl | Medium | 1049.3 | 0 | ||
| BVU | KSAT | San Antonio Intl | KTPA | Tampa Intl | Regional | 842.8 | 1 | ||
| BVU | KSAT | San Antonio Intl | KPHX | Phoenix Sky Harbor Intl | Regional | 730.7 | 1 | ||
| IFR | KSAT | San Antonio Intl | KSFO | San Francisco Intl | Medium | 1285.1 | 1 | ||
| IFR | KSAT | San Antonio Intl | KMSY | New Orleans Intl | Local | 428.5 | 0 | ||
| NAE | KSAT | San Antonio Intl | KTAD | Trinidad - Stokes | Regional | 548.7 | 0 | ||
| OSA | KSAT | San Antonio Intl | KDLF | Del Rio - Laughlin AFB | Local | 121.0 | 1 | ||
| OSA | KSAT | San Antonio Intl | KSAN | San Diego Intl-Lindbergh | Regional | 979.0 | 0 | ||
| OSA | KSAT | San Antonio Intl | KMSY | New Orleans Intl | Local | 428.5 | 0 | ||
| SCA | KSAT | San Antonio Intl | KABE | Allentown - Lehigh Valley Intl | Medium | 1306.7 | 0 | ||
| UFA | KSAT | San Antonio Intl | VHHH | Hong Kong Intl | Long | 7170.8 | 0 | ||
| UFA | KSAT | San Antonio Intl | SBGL | Rio De Janeiro - Galeao-Antonio C Jobim Intl | Long | 4473.0 | 0 | ||
| UFA | KSAT | San Antonio Intl | KDTW | Detroit Metro Wayne Co | Medium | 1054.6 | 0 | ||
| UFA | KSAT | San Antonio Intl | YPDN | Darwin Intl | Long | 7875.9 | 0 | ||
| UFA | KSAT | San Antonio Intl | LFPG | Paris - Charles-De-Gaulle | Long | 4485.1 | 0 | ||
| UFA | KSAT | San Antonio Intl | CYMX | Montreal Intl (Mirabel) | Medium | 1501.5 | 1 | ||
| UPS | KSAT | San Antonio Intl | KATL | The Hartsfield Atlanta Intl | Regional | 758.1 | 1 |