| VA | From | Airport | To | Destination | Type | Distance miles | Frequency | Competitors | |
|---|---|---|---|---|---|---|---|---|---|
| ACF | LKPR | Prague - Ruzyne | LFPG | Paris - Charles-De-Gaulle | Local | 460.1 | 0 | ||
| ACF | LKPR | Prague - Ruzyne | UMMS | Minsk-2 | Regional | 555.9 | 1 | ||
| ACF | LKPR | Prague - Ruzyne | ELLX | Luxembourg | Local | 312.7 | 0 | ||
| ACF | LKPR | Prague - Ruzyne | LFML | Marseille/Provence | Regional | 545.2 | 0 | ||
| ACF | LKPR | Prague - Ruzyne | LPPT | Lisbon | Medium | 1202.8 | 1 | ||
| AEU | LKPR | Prague - Ruzyne | PAFA | Fairbanks Intl | Long | 3854.9 | 1 | ||
| AEU | LKPR | Prague - Ruzyne | EIDW | Dublin Intl | Regional | 785.0 | 0 | ||
| AEU | LKPR | Prague - Ruzyne | EDDF | Frankfurt/Main | Local | 219.1 | 0 | ||
| AEU | LKPR | Prague - Ruzyne | EDDE | Erfurt | Local | 136.5 | 0 | ||
| AEU | LKPR | Prague - Ruzyne | LOWW | Vienna - Schwechat | Local | 150.0 | 0 | ||
| AEU | LKPR | Prague - Ruzyne | EDDP | Leipzig-Halle | Local | 110.5 | 1 | ||
| AEU | LKPR | Prague - Ruzyne | LEPA | Palma De Mallorca | Regional | 798.7 | 0 | ||
| AEU | LKPR | Prague - Ruzyne | LBWN | Varna | Regional | 692.4 | 0 | ||
| EVO | LKPR | Prague - Ruzyne | EDDN | Nürnberg | Local | 128.4 | 0 | ||
| EVO | LKPR | Prague - Ruzyne | EDXW | Westerland/Sylt | Local | 360.3 | 0 | ||
| EVO | LKPR | Prague - Ruzyne | EDDC | Dresden | Local | 64.7 | 0 | ||
| FLW | LKPR | Prague - Ruzyne | LFRS | Nantes/Atlantique | Regional | 652.2 | 2 | ||
| FLW | LKPR | Prague - Ruzyne | LFMN | Nice/Cote dAzur | Local | 481.8 | 1 | ||
| FLW | LKPR | Prague - Ruzyne | LFLL | Lyon - Saint Exupery | Local | 452.4 | 1 | ||
| KSA | LKPR | Prague - Ruzyne | EGNT | Newcastle | Regional | 650.8 | 1 | ||
| OSA | LKPR | Prague - Ruzyne | LPPT | Lisbon | Medium | 1202.8 | 0 | ||
| RSQ | LKPR | Prague - Ruzyne | SBGL | Rio De Janeiro - Galeao-Antonio C Jobim Intl | Long | 5330.6 | 1 | ||
| RSQ | LKPR | Prague - Ruzyne | KBOS | Boston - Logan Intl | Long | 3372.9 | 0 | ||
| TAA | LKPR | Prague - Ruzyne | LZIB | Bratislava - M.R. Stefanik | Local | 163.9 | 0 | ||
| TAA | LKPR | Prague - Ruzyne | LOWW | Vienna - Schwechat | Local | 150.0 | 0 | ||
| TBA | LKPR | Prague - Ruzyne | LUKK | Chisinau | Regional | 612.2 | 0 | ||
| TBA | LKPR | Prague - Ruzyne | LZIB | Bratislava - M.R. Stefanik | Local | 163.9 | 0 | ||
| TCA | LKPR | Prague - Ruzyne | LZIB | Bratislava - M.R. Stefanik | Local | 163.9 | 0 | ||
| TCA | LKPR | Prague - Ruzyne | LOWW | Vienna - Schwechat | Local | 150.0 | 0 | ||
| UFA | LKPR | Prague - Ruzyne | LFPG | Paris - Charles-De-Gaulle | Local | 460.1 | 0 | ||
| UFA | LKPR | Prague - Ruzyne | VHHH | Hong Kong Intl | Long | 4736.9 | 0 | ||
| UFA | LKPR | Prague - Ruzyne | SBGL | Rio De Janeiro - Galeao-Antonio C Jobim Intl | Long | 5330.6 | 0 | ||
| UFA | LKPR | Prague - Ruzyne | KDTW | Detroit Metro Wayne Co | Long | 3785.7 | 0 | ||
| UFA | LKPR | Prague - Ruzyne | YPDN | Darwin Intl | Long | 6987.6 | 0 | ||
| UPS | LKPR | Prague - Ruzyne | EDDH | Hamburg | Local | 264.3 | 0 | ||
| UPS | LKPR | Prague - Ruzyne | EDDL | Dusseldorf | Local | 293.7 | 0 | ||
| UPS | LKPR | Prague - Ruzyne | EDDK | Cologne-Bonn | Local | 275.5 | 0 | ||
| UPS | LKPR | Prague - Ruzyne | EDDF | Frankfurt/Main | Local | 219.1 | 0 | ||
| UPS | LKPR | Prague - Ruzyne | LFPO | Paris - Orly | Local | 470.6 | 0 | ||
| UPS | LKPR | Prague - Ruzyne | LFRS | Nantes/Atlantique | Regional | 652.2 | 0 | ||
| WMF | LKPR | Prague - Ruzyne | EPSY | Szczytno - Szymany | Local | 320.0 | 0 |