| VA | From | Airport | To | Destination | Type | Distance miles | Frequency | Competitors | |
|---|---|---|---|---|---|---|---|---|---|
| CIF | MDPP | Puerto Plata - Gregorio Luperon Intl | LFPG | Paris - Charles-De-Gaulle | Long | 3855.0 | 1 | ||
| CIF | MDPP | Puerto Plata - Gregorio Luperon Intl | PCIS | Canton I - Canton AFLD | Long | 6085.2 | 0 | ||
| JUL | MDPP | Puerto Plata - Gregorio Luperon Intl | MUCA | Ciego De Avila - Maximo Gomez Intl | Local | 480.3 | 1 | ||
| JUL | MDPP | Puerto Plata - Gregorio Luperon Intl | TNCM | St Maarten I - Princess Juliana Intl | Local | 435.8 | 1 | ||
| JUL | MDPP | Puerto Plata - Gregorio Luperon Intl | KMCO | Orlando Intl | Regional | 784.5 | 1 | ||
| JUL | MDPP | Puerto Plata - Gregorio Luperon Intl | TJSJ | San Juan - Luis Munoz Marin Intl | Local | 270.8 | 0 | ||
| KSA | MDPP | Puerto Plata - Gregorio Luperon Intl | EBBR | Brussels National | Long | 3927.3 | 1 | ||
| KSA | MDPP | Puerto Plata - Gregorio Luperon Intl | LEIB | Ibiza | Long | 3836.6 | 1 | ||
| KSA | MDPP | Puerto Plata - Gregorio Luperon Intl | MPBO | Bocas Del Toro Intl | Regional | 921.5 | 0 | ||
| PIA | MDPP | Puerto Plata - Gregorio Luperon Intl | TNCM | St Maarten I - Princess Juliana Intl | Local | 435.8 | 1 | ||
| RSQ | MDPP | Puerto Plata - Gregorio Luperon Intl | EDDF | Frankfurt/Main | Long | 4086.0 | 0 | ||
| RSQ | MDPP | Puerto Plata - Gregorio Luperon Intl | EDDP | Leipzig-Halle | Long | 4215.6 | 1 |