| VA | From | Airport | To | Destination | Type | Distance miles | Frequency | Competitors | |
|---|---|---|---|---|---|---|---|---|---|
| RED | MDST | Santiago City - Cibao Intl | KBOI | Boise Air Term | Medium | 2700.5 | 0 | ||
| UCA | MDST | Santiago City - Cibao Intl | TISX | St Croix I - Henry E Rohlsen | Local | 345.7 | 0 | ||
| UCA | MDST | Santiago City - Cibao Intl | MYEF | Great Exuma I - Exuma Intl | Local | 385.8 | 1 |