| VA | From | Airport | To | Destination | Type | Distance miles | Frequency | Competitors | |
|---|---|---|---|---|---|---|---|---|---|
| CIF | MHLM | San Pedro Sula - La Mesa Intl | LFPG | Paris - Charles-De-Gaulle | Long | 4722.1 | 1 | ||
| CIF | MHLM | San Pedro Sula - La Mesa Intl | NWWW | Noumea - Tontouta | Long | 6607.6 | 0 | ||
| IFR | MHLM | San Pedro Sula - La Mesa Intl | MTPP | Port-Au-Prince Intl | Regional | 915.7 | 0 | ||
| UFA | MHLM | San Pedro Sula - La Mesa Intl | LFPG | Paris - Charles-De-Gaulle | Long | 4722.1 | 0 | ||
| UFA | MHLM | San Pedro Sula - La Mesa Intl | YPDN | Darwin Intl | Long | 8536.1 | 0 | ||
| UFA | MHLM | San Pedro Sula - La Mesa Intl | SBGL | Rio De Janeiro - Galeao-Antonio C Jobim Intl | Long | 3485.6 | 0 | ||
| UFA | MHLM | San Pedro Sula - La Mesa Intl | VHHH | Hong Kong Intl | Long | 8196.0 | 0 | ||
| UFA | MHLM | San Pedro Sula - La Mesa Intl | KDTW | Detroit Metro Wayne Co | Medium | 1622.8 | 0 | ||
| USA | MHLM | San Pedro Sula - La Mesa Intl | KIAH | Houston - G Bush Intercontinental/Houst | Regional | 963.0 | 1 | ||
| USA | MHLM | San Pedro Sula - La Mesa Intl | MUVR | Varadero - Juan G. Gomez Intl | Regional | 584.6 | 0 |