| VA | From | Airport | To | Destination | Type | Distance miles | Frequency | Competitors | |
|---|---|---|---|---|---|---|---|---|---|
| NAE | MMIO | Saltillo - Plan De Guadalupe Intl | KVQQ | Jacksonville - Cecil | Medium | 1047.0 | 0 | ||
| NAE | MMIO | Saltillo - Plan De Guadalupe Intl | KSAN | San Diego Intl-Lindbergh | Regional | 953.4 | 0 | ||
| NAE | MMIO | Saltillo - Plan De Guadalupe Intl | PHNL | Honolulu Intl | Long | 3124.5 | 0 | ||
| NAE | MMIO | Saltillo - Plan De Guadalupe Intl | RCTP | Taipei - Chiang Kai Shek Intl | Long | 6901.1 | 1 | ||
| NAE | MMIO | Saltillo - Plan De Guadalupe Intl | KSFO | San Francisco Intl | Medium | 1308.7 | 2 |