| VA | From | Airport | To | Destination | Type | Distance miles | Frequency | Competitors | |
|---|---|---|---|---|---|---|---|---|---|
| CFC | MPHO | Balboa - Howard AFB | EHAM | Amsterdam - Schiphol | Long | 4770.9 | 2 | ||
| CFC | MPHO | Balboa - Howard AFB | MPTO | Panama City - Tocumen Intl | Local | 15.7 | 2 | ||
| CFC | MPHO | Balboa - Howard AFB | MSLP | San Salvador - El Salvador Intl | Regional | 619.5 | 6 | ||
| EVO | MPHO | Balboa - Howard AFB | OMAA | Abu Dhabi Intl | Long | 7457.9 | 0 | ||
| EVO | MPHO | Balboa - Howard AFB | EDDF | Frankfurt/Main | Long | 4920.4 | 1 | ||
| EVO | MPHO | Balboa - Howard AFB | MHTG | Tegucigalpa - Toncontin Intl | Regional | 544.0 | 0 | ||
| RSQ | MPHO | Balboa - Howard AFB | SBGL | Rio De Janeiro - Galeao-Antonio C Jobim Intl | Medium | 2860.1 | 0 | ||
| RSQ | MPHO | Balboa - Howard AFB | FHAW | Ascension I. - Ascension Aux AB | Long | 4027.0 | 0 | ||
| RSQ | MPHO | Balboa - Howard AFB | GCLP | Gran Canaria | Long | 3786.4 | 0 | ||
| RSQ | MPHO | Balboa - Howard AFB | KSEA | Seattle-Tacoma Intl | Long | 3166.1 | 1 | ||
| RSQ | MPHO | Balboa - Howard AFB | SBNT | Natal - Augusto Severo Intl | Medium | 2797.5 | 1 | ||
| SKA | MPHO | Balboa - Howard AFB | EHAM | Amsterdam - Schiphol | Long | 4770.9 | 1 | ||
| TKA | MPHO | Balboa - Howard AFB | NZAA | Auckland Intl | Long | 6467.6 | 0 | ||
| TKA | MPHO | Balboa - Howard AFB | EHAM | Amsterdam - Schiphol | Long | 4770.9 | 0 | ||
| TKA | MPHO | Balboa - Howard AFB | RJGG | Chubu Centrair International | Long | 7459.6 | 1 |