| VA | From | Airport | To | Destination | Type | Distance miles | Frequency | Competitors | |
|---|---|---|---|---|---|---|---|---|---|
| AAA | MSSS | San Salvador - Ilopango Intl | MHTG | Tegucigalpa - Toncontin Intl | Local | 112.8 | 2 | ||
| AAA | MSSS | San Salvador - Ilopango Intl | MGRT | Retalhuleu | Local | 158.0 | 0 | ||
| AEU | MSSS | San Salvador - Ilopango Intl | EDDF | Frankfurt/Main | Long | 5062.6 | 1 | ||
| AEU | MSSS | San Salvador - Ilopango Intl | EDDT | Berlin - Tegel | Long | 5189.7 | 0 | ||
| AVL | MSSS | San Salvador - Ilopango Intl | MHTG | Tegucigalpa - Toncontin Intl | Local | 112.8 | 2 | ||
| AVL | MSSS | San Salvador - Ilopango Intl | MGRT | Retalhuleu | Local | 158.0 | 0 | ||
| CFC | MSSS | San Salvador - Ilopango Intl | MSLP | San Salvador - El Salvador Intl | Local | 15.5 | 7 | ||
| CFC | MSSS | San Salvador - Ilopango Intl | MGRT | Retalhuleu | Local | 158.0 | 2 | ||
| CFC | MSSS | San Salvador - Ilopango Intl | MHTG | Tegucigalpa - Toncontin Intl | Local | 112.8 | 3 | ||
| CIF | MSSS | San Salvador - Ilopango Intl | LFPG | Paris - Charles-De-Gaulle | Long | 4846.8 | 0 | ||
| CIF | MSSS | San Salvador - Ilopango Intl | NFTF | Nukualofa - Fuaamotu Intl | Long | 5479.0 | 1 | ||
| EVO | MSSS | San Salvador - Ilopango Intl | MSLP | San Salvador - El Salvador Intl | Local | 15.5 | 0 | ||
| EVO | MSSS | San Salvador - Ilopango Intl | MGQZ | MGQZ | Local | 155.4 | 0 | ||
| EVO | MSSS | San Salvador - Ilopango Intl | MGPB | Puerto Barrios | Local | 125.9 | 1 | ||
| FTS | MSSS | San Salvador - Ilopango Intl | MHTG | Tegucigalpa - Toncontin Intl | Local | 112.8 | 1 | ||
| FTS | MSSS | San Salvador - Ilopango Intl | MGRT | Retalhuleu | Local | 158.0 | 0 | ||
| JUL | MSSS | San Salvador - Ilopango Intl | MHTG | Tegucigalpa - Toncontin Intl | Local | 112.8 | 1 | ||
| JUL | MSSS | San Salvador - Ilopango Intl | MGRT | Retalhuleu | Local | 158.0 | 0 | ||
| KSA | MSSS | San Salvador - Ilopango Intl | MHTG | Tegucigalpa - Toncontin Intl | Local | 112.8 | 1 | ||
| KSA | MSSS | San Salvador - Ilopango Intl | MGRT | Retalhuleu | Local | 158.0 | 0 | ||
| SAA | MSSS | San Salvador - Ilopango Intl | MHTG | Tegucigalpa - Toncontin Intl | Local | 112.8 | 1 | ||
| SKA | MSSS | San Salvador - Ilopango Intl | MGRT | Retalhuleu | Local | 158.0 | 0 | ||
| SKA | MSSS | San Salvador - Ilopango Intl | MHTG | Tegucigalpa - Toncontin Intl | Local | 112.8 | 1 | ||
| TKA | MSSS | San Salvador - Ilopango Intl | MHTG | Tegucigalpa - Toncontin Intl | Local | 112.8 | 1 | ||
| TKA | MSSS | San Salvador - Ilopango Intl | MGRT | Retalhuleu | Local | 158.0 | 0 | ||
| USA | MSSS | San Salvador - Ilopango Intl | MGRT | Retalhuleu | Local | 158.0 | 0 | ||
| USA | MSSS | San Salvador - Ilopango Intl | MHTG | Tegucigalpa - Toncontin Intl | Local | 112.8 | 1 |