| VA | From | Airport | To | Destination | Type | Distance miles | Frequency | Competitors | |
|---|---|---|---|---|---|---|---|---|---|
| ACF | MWCR | Grand Cayman - Roberts Intl | LFML | Marseille/Provence | Long | 4466.9 | 0 | ||
| CIF | MWCR | Grand Cayman - Roberts Intl | LFPG | Paris - Charles-De-Gaulle | Long | 4298.0 | 0 | ||
| CIF | MWCR | Grand Cayman - Roberts Intl | NSTU | Pago Pago Intl | Long | 5645.8 | 1 | ||
| NAE | MWCR | Grand Cayman - Roberts Intl | KPIT | Pittsburgh Intl | Medium | 1273.3 | 0 | ||
| NAE | MWCR | Grand Cayman - Roberts Intl | TFFR | Pointe-A-Pitre - Le Raizet | Medium | 1146.9 | 2 | ||
| RSQ | MWCR | Grand Cayman - Roberts Intl | SEQM | Quito Aeropuerto Internacional Mariscal Sucre | Medium | 1178.9 | 0 |