| VA | From | Airport | To | Destination | Type | Distance miles | Frequency | Competitors | |
|---|---|---|---|---|---|---|---|---|---|
| RSQ | SEQM | Quito Aeropuerto Internacional Mariscal Sucre | BGBW | Narsarsuaq | Long | 3975.0 | 1 | ||
| RSQ | SEQM | Quito Aeropuerto Internacional Mariscal Sucre | MWCR | Grand Cayman - Roberts Intl | Medium | 1178.9 | 0 | ||
| RSQ | SEQM | Quito Aeropuerto Internacional Mariscal Sucre | SLLP | La Paz - El Alto Intl | Medium | 1153.0 | 0 | ||
| SKA | SEQM | Quito Aeropuerto Internacional Mariscal Sucre | KTPA | Tampa Intl | Medium | 1703.6 | 1 | ||
| SKA | SEQM | Quito Aeropuerto Internacional Mariscal Sucre | SEQM | Quito Aeropuerto Internacional Mariscal Sucre | Local | 0.0 | 0 | ||
| SKA | SEQM | Quito Aeropuerto Internacional Mariscal Sucre | SBKP | Campinas - Viracopos Intl | Medium | 2280.1 | 1 | ||
| SKA | SEQM | Quito Aeropuerto Internacional Mariscal Sucre | PANC | Stevens Anchorage Intl | Long | 4882.8 | 0 | ||
| SKA | SEQM | Quito Aeropuerto Internacional Mariscal Sucre | SBSV | Salvador - Dep. L. E. Magalhaes Intl | Medium | 2501.5 | 1 | ||
| SKA | SEQM | Quito Aeropuerto Internacional Mariscal Sucre | KMSY | New Orleans Intl | Medium | 1931.3 | 0 | ||
| SKA | SEQM | Quito Aeropuerto Internacional Mariscal Sucre | KSAN | San Diego Intl-Lindbergh | Medium | 2949.0 | 0 | ||
| SKA | SEQM | Quito Aeropuerto Internacional Mariscal Sucre | TJSJ | San Juan - Luis Munoz Marin Intl | Medium | 1331.7 | 1 | ||
| SKA | SEQM | Quito Aeropuerto Internacional Mariscal Sucre | SCEL | Santiago - Arturo Merino Benitez Intl | Medium | 2040.6 | 1 | ||
| SKA | SEQM | Quito Aeropuerto Internacional Mariscal Sucre | SBGL | Rio De Janeiro - Galeao-Antonio C Jobim Intl | Medium | 2458.8 | 0 |